Our Technology

Our Product

Mitralign has developed a proprietary mitral valve repair system (“Mitralign Percutaneous Annuloplasty System”) which mimics surgical suture annuloplasty and aims to plicate the dilated posterior mitral valve annulus in patients with functional mitral regurgitation. The Mitralign Percutaneous Annuloplasty System, in essence, is a set of the following devices: deflectable guide catheter, steerable wire-delivery catheter, crossing wires, “Bident” translational catheter, pledget delivery catheters pre-loaded with pledget, plication catheter pre-loaded with lock, and suture cutter.

Our Procedure

The Mitralign system is designed for femoral access (14 Fr.) and approaches the posterior mitral annulus via the left ventricle. A steerable catheter with a deflectable end is delivered via 12.5 Fr. guide catheter between the papillary muscles facing posterior mitral annulus. The steerable catheter and a two-arm (bident) catheter help placing two pairs of wires through the mitral annulus at the P1 and P3 locations. Once the wire pair is placed at one location, surgical pledgets are delivered over the wires and anchored across the posterior mitral annulus from the left atrium to the left ventricle. The surgical pledgets are tethered and put into tension to decrease the annulus circumference, and the achieved mitral annulus plication is locked in place. Once the entire procedure is completed at one location, the next wire pair is then placed at the other scallop location (P1 or P3) and the implant process is completed. The procedure aims to decrease mitral annulus circumference and septal-lateral dimension of the mitral valve, thereby reducing mitral regurgitation severity significantly.

This device is currently in clinical investigations outside the United States.

This material is intended to provide general information, including opinions and recommendations, contained herein for educational purposes only. Such information is not intended to be a substitute for professional medical advice, diagnosis or treatment. The material is not intended to direct clinical care in any specific circumstance. The judgment regarding a particular clinical procedure or treatment plan must be made by a qualified physician in light of the clinical data presented by the patient and the diagnostic and treatment options available.